The comparison of chemical content and bioactive capacity of domestic and import Hypericum perforatum aqueous extracts

Hypericum perforatum, known as St. John's Wort and most used ethnaformacolgically, belongs to the Hypericaceae family. In this work, we aimed evaluate antioxidant, antimicrobial, DNA protective activities, enzyme inhibitor properties of domestic import H. perforatum aqueous extracts. The total phenolic flavonoid contents were also determined for both samples. Results exhibited a high content Domestic extract (DHPE) Import (IHPE) Meanwhile, inhibition activity levels α-glucosidase remarkable, IC50 value DHPE was 16.35±0.07 µg/mL, IHPE 15.05±1.36 samples demonstrated almost twice standard effect (IC50: 30.62±2.07 µg/mL). Moreover, against α-amylase more effective than acarbose. antibacterial results follows; highest MIC detected by 64 µg/mL B. cereus. addition, shown be sample all microorganisms. Furthermore, good from oxidative H2O2-induced damage. Both tested had an abundance in inhibitory diabetic enzymes. Generally, bioactivity tests’ appeared quite compared standards.